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Ketamine: Effects, Hazards & Overdose


Ketamine is a liquid medicine that helps in the treatment of pain by injecting and maintaining anesthesia. It delivers sedation in the body and provides relaxation and alertness. Other than that, it helps to deal with depression and anxiety

Ketamine is a very primitive medication used in wars and on the battlefield. Since the 1970s, it has been widely prescribed medicine in the USA in the form of injected anesthesia.

It belongs to a drug class known as dissociative anesthetics. It is also known as Ketalar, Ketanest, and Ketaset. Besides that, the medicine has some chemical composition of hallucinogen, phencyclidine (PCP), dextromethorphan, and laughing gas or nitrous oxide.


How does it work?


Ketamine starts working in 5 to 15 minutes, and this one is used during operation and surgeries. The sedation of ketamine is lasting longer than 25 minutes. 


What are the dosages of Ketamine?


It comes in multiple forms and dosages, including 75 to 125 mg by the Intramuscular (IM) route or subcutaneous injection. Secondly, 60 to 250 mg is given using the Insufflation route (intranasal or “snorting”). Moreover, the Intravenously (IV) route is available in a dose of 50 to 100 mg. Lastly, you can take ketamine through the mouth in the dose of 200 to 300 mg.


Side Effects & Health Hazards of Ketamine


Ketamine brings both short-term and permanent adverse effects, including:


Temporary side-effects:


  • Problem in attention
  • Learning issues and Memory loss
  • Hallucination 
  • Confusion
  • Sedative 
  • Memory loss
  • High blood pressure
  • Lack of consciousness
  • Slow breathing

These types of side-effects can disappear within 2-3 days. But, if they become intolerable, then get a different medication to treat that.


Permanent/long-term side-effects:


  • Ulcer
  • Bladder pain
  • Problem in kidney
  • Stomach pain
  • Poor memory
  • Depression and anxiety

These are the causes of severe problems by Ketamine medicine that requires instant medical attention.




The main use for ketamine is to provide medical and veterinarian anesthetics. Ketamine helps you lower or remove the pain when you are getting treatment for injuries or surgeries.

Ketamine comes from a family of drugs known as dissociative anesthetics. It is either injected into the muscle or given as an intravenous line for medical purposes.


It is used in procedures like 


  • Orthopedic procedures 
  • Minor surgeries 
  • Skin grafts 
  • Cardiac catheterization 
  • Diagnostic procedures

Ketamine can also be used as a painkiller if used in a lower dose.

It can also be used in emergency situations like wars, disaster zones, or in poor countries because it does not require oxygen, electric supply, or any trained staff. 




There are multiple scenarios when ketamine can cause harm to its users. You should only use ketamine as prescribed by the doctor.

Ketamine is a potent anesthetic that is abused by many people. So to use it properly there are precautions that you should follow.


Tell your doctor if you have conditions like:


  • Do not take ketamine if you are allergic to it.
  • High blood pressure 
  • Liver disease 
  • Heart disease 
  • Alcoholism 
  • Are pregnant or breastfeeding.

Anesthetics can create issues in brain development in young children or unborn children. It can create learning and behavior pattern problems in them.

Consult your doctor before you breastfeed because ketamine can travel through breastmilk and harm your infant.


Addiction and abuse 


Ketamine is often abused by many people. Individuals use it as a party drug because it creates a euphoric effect that makes you feel like you are floating out of your body.

It can also cause hallucinating effects that are similar to LSD.

Ketamine is misused in different ways such as 

  • Snorting 
  • Smoked with tobacco or marijuana 
  • Mixed with drinks 

Regardless of the method, the onset of the effects takes about minutes and stays for about an hour.


Some adverse effects of abuse


  • Seizures 
  • High blood pressure 
  • Respiratory problems 
  • High blood pressure
  • Addiction
  • Psychosis 
  • Hallucinations 

There are not many severe medical issues but because of the effects and high levels, it produces it can make you prone to accidental injuries.




Ketamine is a popular medicine in medical history and part of medical treatment. It has multiple functions, such as depression treatment and pain relief. By looking at its history, ketamine used in wars to prevent pain on a battlefield. Therefore, you need to ask your doctor before taking this.




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